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Rethinking Checkpoint Blockade for Cancer Treatment

Vycellix Sweden is a contributing member of the REPRESSIT Consortium with the grant-funded mission to generate a technology platform for off-the-shelf RIPR molecules (Receptor Inhibition by Phosphatase Recruitment) targeting any tyrosine phosphatase carrying inhibitory immune receptor.

Link to Nature Publication:  https://www.nature.com/articles/s41586-020-2851-2

Our REPRESSIT Consortium aims to generate Proof-of-Concept for full in vivo functionality of RIPR molecules against diverse T and NK cell receptors in preclinical tumor models.

Our goal is to pioneer the development of next-generation checkpoint therapeutics with unprecedented efficacy for as broad a population of cancer patients in need as possible.

For more details on the REPRESSIT program, please visit:  https://www.repressit.eu/